Liposomes are drug delivery vehicles Liposomes are prepared artificial vesicles composed of lipid bilayer. They can be used as a vehicle for the delivery of nutrients and drugs. Liposomes are prepared by disrupting biological membranes using sonication. Liposomes are closed vehicles that contain both a lipophilic and a hydrophilic region. The formation of these vesicles occurs by hydrating a mixture of cholesterol and a phospholipid. There are many different approaches to administering these drugs. Improvements in the performance of drug molecules result from delayed elimination from circulation, protection of the drug from the environment, and limitation of effects on target cells. “Liposomes were discovered about 40 years ago by Bangham and his colleague.” (Boddyreddy, 2012) which was an accidental discovery because he was studying blood clotting. Liposome structures are spherical and usually have a diameter between 15 nm and 1000 nm. They are able to target ligands attached to their surface to direct them to the appropriate sites...
tags