Cancer regression caused by the release of 1,25-dihydroxyvitamin D3 could lead to a new class of cancer therapies. The goal is to provoke a sarcoidosis response against a malignant process. This approach probably represents one of the most effective therapeutic options because it uses an existing biological system. Vitamin D is the key to kickstarting this EPOCA system. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay Vitamin D deficiency is associated with increased mortality in Germany. We calculated an associated mortality rate of 18,000 lives lost each year [166]. The EPOCA theory presented here is a causal explanation for this large number. Without a sufficient amount of vitamin D, the substrate for blocking tumor cells is missing. Therefore, the administration of vitamin D can be considered an effective measure to prevent cancer. The essential ideas of the EPOCA theory were presented at the 4th International Symposium on Vitamin D and Analogues in Cancer Prevention and Therapy in Homburg (Saar) in 2011. This was followed by another presentation on the Vitamin D Update 2013 congress in Berlin. The EPOCA hypothesis concerns several areas of medical practice. The first area is pulmonology, whose professionals treat patients with sarcoidosis. We must also consider the oncologists who diagnose and treat cancer. The third area involves vitamin D researchers studying the relationship between vitamin D and defense against cancer. Even in modern science, new discoveries can remain hidden for a long time because they arouse negative emotions. Having researchers abandon their traditional work area and invade neighboring areas can be burdensome. Therefore, the interdisciplinary perspective of EPOCA theory brings additional stress to those who deal with it. Everyone is inclined to quickly retreat into their own comfortable territory: it is difficult to publish scientific statements regarding a nearby area. A second stress arises, through a problematic change in the patient's perspective. When the EPOCA theory is presented to sarcoidosis patients, they are confronted with the idea of ​​uncontrolled cell proliferation: “cancer” causes the symptoms of sarcoidosis. This new perspective is not trivial. The doctor should moderate the patient's psychological stress with facts. First, the prognosis of sarcoidosis with a 97% cure is an excellent answer. According to EPOCA theory, this observed reaction is a reliable physiological work. A psychological advantage of the EPOCA theory is that it eliminates anxiety about a mysterious illness. The result of this discussion is the prospect of a cure in the near future. It is very important that this understanding provides a new and successful approach to therapy. To date, therapeutic success with the preferred cortisone therapy has been inconsistent. The reason for this is attributed to the lack of perception of vitamin D levels. In the EPOCA theory, vitamin D is an essential component for healing and shortening the course of sarcoidosis. Even if the patient with sarcoidosis is faced with the idea of ​​a malignant disease, it is useful to know that the cause of this disease is clarified and that a manageable solution to the chronic course exists. How might a doctor communicate the confirmed diagnosis of sarcoidosis? We have collected our ideas in the following draft touching on all four important aspects. Imagine there is a physiological response to a disease! "" I have good news about your health. Your body is showing symptoms of so-called sarcoidosis. By reacting this way your body has proven that it is enough